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TLC was immediately set up to go into the studio with Reid and Edmonds, Dallas Austin, Jermaine Dupri, and Marley Marl producing their first album.
The new trio debuted as backing vocalists on "Rebel (With a Cause)", a track on Jermaine Jackson's sole album for La Face, You Said (1991). On the TLC Tip, was released on February 25, 1992, by La Face/Arista Records.
During TLC's first national tour, as MC Hammer's opening act, Lopes and Thomas discovered that Watkins had sickle-cell anemia, an ailment which she kept a closely guarded secret until she became very ill while TLC was touring the Southwest US.
Watkins continued to battle her condition and eventually became a spokesperson for the Sickle Cell Disease Association of America in the late 1990s.
TLC is an American girl group whose original line-up consisted of Tionne "T-Boz" Watkins, Lisa "Left Eye" Lopes and Rozonda "Chilli" Thomas.